Shouldn't do ~ as long as you wear the mask and change the filter regular like.
Mask and filter you say...?
It's all to do with particle size ~ some that you breath in will pass through unhindered but some will lodge in the lungs (Blue asbestos being a prime example. Grey asbestos is a different particle size and thus no danger) Same with some additives in Weathershield paint. I think that some products of that type do recommend a mask and filter to cover mouth and nose.
Pauses whilst some Jackass comes up with a picture of a Lone Ranger mask or a WWII Respirator.